DOWNLOADS
Articles, preprints and posters
In the publications section you can find links to articles, preprints and posters.Slides
Estimation of metabolic fluxes when measurements are insufficient and/or uncertain. J. Picó and F. Llaneras, Meeting of the spanish network of systems biology, 2007.
These slides provide a good summary of the flux spectrum approach and its applications [1, 2].Software
Flux spectrum approach matlab package.
The package contains two matlab functions to compute the flux spectrum and a example [1, 2, 3].still not available... Metabolic flux analysis.
A simple implementation of metabolic flux analysis. It is also useful to divide the stoichiometric matrix in the measured and unknown parts (in order to analyze its determinacy and redundancy) [1].still not available... Alpha-spectrum.
Two matlab functions to compute the alpha-spectrum considering measurements uncertainty, and a simple example [2].still not available... Convert measured concentrations into measured fluxes.
A set of simple function useful to convert measured concentrations into measured fluxes: euler methods, non-linear observer, mean average methods, etc [1].still not available... C# vectors library.
A very simple library with classes representing mathematical vectors in a suitable way. It inherits from the class Arraylist, so it is not necessary to define the vector length a priori [4].DEA Dissertation
This dissertation describes my research during the first stages of my PhD. It has two main parts, the first one devoted to the state-of-the-art [5] and the second one to my first contributions [1, 2]. The slides provide a short summary of my work during the DEA period and a introduction to my research (in spanish).
still not available... Main document.
still not available... Slides.
REFERENCES
[1] Llaneras F, Picó J. A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient. BMC Bioinformatics, 2007, 8:421[article - free open access]
[2] Llaneras F, Picó J. An interval approach for dealing with flux distributions and elementary modes activity patterns. Journal of Theoretical Biology, 2007, 246(2): 290-308.
[article] [preprint]
[3] Llaneras F, Bastin G., Picó J: On metabolic flux analysis when measurements are insufficient and/or uncertain: the flux spectrum and the flux space. IAP Dysco workshop, Belgium, 2007.
[poster]
[4] F. Llaneras, J. Picó, J. L. Navarro, E. Picó-Marco. Diseño E Implementación de un Entorno Gráfico de Simulación, Monitorización y Control de Biorreactores (spanish). XXVI Jornadas De Automática, Eds: F. Torres, Q. Reinoso, ISBN: 84-689-0703-8, 2005.
[article] [poster]
[5] Llaneras F, Picó J. Stoichiometric modelling of the cell metabolism. Journal of Bioscience and Bioengineering, (In press).